The Effectiveness of AI-Assisted Diagnostic Tools in Early Detection of Cardiovascular Diseases
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Keywords

AI-assisted diagnostics
Early detection
Cardiovascular disease
Wearable monitoring

Abstract

Early detection of cardiovascular diseases (CVDs) is crucial for reducing morbidity and mortality. Artificial intelligence (AI)–assisted diagnostic tools—spanning deep-learning analysis of electrocardiograms (ECGs), AI interpretation of coronary CT angiography (CCTA), machine-learning risk stratification, and wearable-based predictive monitoring—have rapidly advanced and begun entering clinical workflows. This article critically evaluates the effectiveness of current AI tools for early CVD detection, comparing diagnostic accuracy, clinical utility, regulatory progress, and real-world performance. We synthesize evidence from algorithm validation studies, clinical trials, and real-world deployments, discuss limitations (bias, data quality, integration barriers), and outline practical recommendations for safe, equitable implementation in routine care.

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References

Asselbergs, F. W., et al. (2021). Artificial intelligence in cardiology: the debate continues. European Heart Journal - Digital Health. OUP Academic

Ansari, Y., et al. (2023). Deep learning for ECG arrhythmia detection: survey and perspectives. Journal of Healthcare Engineering. PMC

Murat, F., et al. (2021). Review of deep learning–based atrial fibrillation detection using ECG. International Journal of Environmental Research and Public Health. MDPI

Mastrodicasa, D., et al. (2025). Use of AI in cardiac CT and MRI: a scientific statement. Radiology (multisociety statement). RSNA Publications

Betancur, J., et al. (2022). Deep learning myocardial perfusion imaging and CAD detection — comparative study. Journal of Nuclear Cardiology. healthcare-bulletin.co.uk

Hadida Barzilai, D., et al. (2025). Randomized controlled trials evaluating AI in cardiovascular care: systematic review. JACC: Advances. JACC

Yu, T., et al. (2025). Enhancing cardiac disease detection via fusion of machine learning and medical image analysis. Scientific Reports. Nature

Velandia, H., et al. (2025). Systematic review: AI-ECG applications for early detection of cardiovascular disease. Biosensors / MDPI. MDPI

Czerwinski, A., et al. (2025). Interpretable arrhythmia detection using deep learning ensembles and XAI. npj Digital Medicine. Nature

Wu, Z., et al. (2025). Deep learning and electrocardiography: systematic review of architectures and clinical tasks. BioMedical Engineering OnLine. SpringerLink

Tripathi, S., et al. (2025). Cardiothoracic imaging AI for cardiac diseases: imaging biomarkers and detection. Clinical Radiology / Elsevier. ScienceDirect

Marey, A., et al. (2025). From echocardiography to CT/MRI: AI diagnostic performance across modalities. PubMed Central (review). PMC

Jin, Y., et al. (2025). Explainable paroxysmal atrial fibrillation diagnosis using deep learning on ECG. Korean Journal of Internal Medicine. KJIM

Pushadapu, V. V., et al. (2025). Artificial Intelligence and Machine Learning: diagnostic devices for early CVD detection. Machine Learning in Healthcare. SpringerLink

Nakamura, T., et al. (2022). Artificial intelligence and cardiology: current status and future directions. Cardiology Journals / Elsevier. ScienceDirect

Nzeako, T. R., et al. (2025). Artificial intelligence in interventional cardiology: review of diagnostic and procedural roles. PMC Article. PMC

Gunjal, A., et al. (2025). A comprehensive survey of AI methods for improving CVD diagnosis. Journal of Biomedical Informatics / ScienceDirect. ScienceDirect

Tayyeb, M., et al. (2023). Deep learning approach for automatic cardiovascular disease prediction: model and evaluation. Computers in Biology and Medicine. ScienceDirect

(News / translational) Coverage of AI-ECG tools (Aire / EchoNext / wearable-AI studies) — reporting on large-scale ECG-trained models for early structural heart disease detection. The Guardian / Financial Times / NYPost summaries. The Guardian+2Financial Times+2

Comprehensive review: “Artificial intelligence in cardiovascular diagnostics” — review synthesizing diagnostic accuracy, clinical readiness, and challenges (bias, validation, regulation). PubMed Central review (2025). PMC

Ahmad, N. R. (2024). Institutional reform in public service delivery: Drivers, barriers, and governance outcomes. Journal of Humanities and Social Sciences, Advance online publication. https://doi.org/10.52152/jhs8rn12

Ahmad, N. R. (2025). Urban water service delivery in emerging economies: Fiscal sustainability, cost recovery, and governance performance. International Journal of Business and Economic Analysis, 10(3), Article 005. https://doi.org/10.24088/IJBEA-2025-103005

Irk, E. (2025). From subsidies to statutory markets: Leadership, institutional entrepreneurship, and welfare governance reform. Lex Localis – Journal of Local Self Government, 23(S6), 9549–9566. https://doi.org/10.52152/s59sjh53

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Copyright (c) 2024 Saima Parveen, Omar Saeed (Author)

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